11/23/2023 0 Comments Disease Infected: Plague downloadpestis with ectoparasite transmissibility while maintaining its enteric transmissibility. pestis genomes recovered from affected archaeological sites have suggested clonal evolution from a common ancestor shared with the closely related enteric pathogen Yersinia pseudotuberculosis and have indicated that ymt gene acquisition during the Bronze Age conferred Y. Plague is acknowledged to have infected human populations for at least 5,000 years in Eurasia. Mandatory primary prevention relies on the active surveillance of established plague foci and ectoparasite control. Point-of-care diagnosis, early antibiotic treatment, and confinement measures contribute to outbreak control despite residual mortality. Finally, the rarely reported consumption of contaminated raw meat causes pharyngeal and gastrointestinal plague. In contrast, droplet inhalation after close contact with infected mammals induces primary pneumonic plague. Transmission from one host to another relies mainly on infected flea bites, inducing typical painful, enlarged lymph nodes referred to as buboes, followed by septicemic dissemination of the pathogen. pestis-contaminated soils, burrowing and nonburrowing mammals exhibiting variable degrees of plague susceptibility, and their associated fleas. ![]() Its persistence in the environment relies on the subtle balance between Y. The Gram-negative bacterium Yersinia pestis is responsible for deadly plague, a zoonotic disease established in stable foci in the Americas, Africa, and Eurasia.
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